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Upstream Process Development P有從latform

Service Introduction 們煙

Media and feed screenin匠見g platform
Protein Quality A舊輛ssessment (charge variants, 讀紙glycosylationand aggregat公腦es)
Stirred bioreactor p議市rocess development
Orbital Shaken長站 bioreactor process developme視房nt
Perfusion process pl看自atform
Intensified Fed-b風工atch culture


Stirred Cell Culture Pla那醫tform

TOP cloning bioreactor cult跳到uring evaluation, 3-15L scale culturin照化g process development sys睡去tem.

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Orbital Shaken Cell Cultu紅高re Platform

The novel bio-r朋員eacting and amplification sy短算stem isjointly developed between Can我都ton Biologics and th綠短e world's top bioreactor su舞南pplier Kuhner. It is more suita子還ble for shear-sensitive 說和protein manufacturing, p信醫roviding a more stab爸又le culturing environment for e個家asily degradable and 跳哥easy-to-aggregate proteins. The sys關數tem has excellent scal志街e-up consistency from lab scale to b不什atch manufacturing scale. 的上

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Downstream Process Development光內 Platform

  • I. McAb Purification 服外

    Conventional affinity chromatogr人都aphy purification 是年
    Cost effective purification w/o文紙 affinitychromatography
    Membrane chromatograph煙拍y purification
  • II. BsAb Purification 市師

    Aggregate removal 好歌
    Product relate件船d impurities removal樹飛 (mismatched and incomplet影兵e antibody fragments)煙劇
    Mild purification condition to maximize protein stabilit外兵y
  • III. Recombinant 物慢protein purification

    Diversified virus ina火件ctivation protocols 銀他
    Appropriate protein capture strategi開吃es
    Multiple protocols to maximize protein stability
  • Standard

    Follow CDE and ICH Guideli頻黑ne
    Utilize QbD development c雨體oncepts
    Apply HTPD and DOE tools
  • Technology

    Chomatography techniques門數
    Filtering technology
    Virus inactivation/removal t輛吧echnology
  • Advantages

    Recombinant protein purifica光校tion
    Bispecific antibody purification 在車
    Maximum protein stability
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Liquid Formulation Dev機票elopment Platform

Liquid Formula了有tion Development Platform 生舞

Rich project experience and st南金rong regulatory track record 自文
High-throughput analytical做短 technology for fast formulation scree家嗎ning
Particle broad-spectrum子視 detection

Lyophilization Formula說分tion Development Plat日唱form

Quick solution t行慢o develop stable formulation區北
Lyophilization process 飛草development
Testing of critical f是爸ormulation temperature
Determination of water content 舞什

Inhalation Formulation 自大Development Platform

Innovative delivery of麗還 inhaled biologics 唱村
Inhalation formulation devel在話opment
Nebulizer screening
Inhaled aeroso鐘體l characterization
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